The First Affiliated Hospital of Jinan University (also known as Guangzhou Overseas Chinese Hospital and the First Clinical Medical College of Jinan University) is a directly affiliated hospital of Jinan University, a national "Double First-Class" university — the "highest institution of learning for overseas Chinese" — jointly established by the United Front Work Department of the CPC Central Committee, the Ministry of Education and Guangdong Province. As a comprehensive top-tier Grade III-A hospital integrating medical care, teaching, research, prevention, health care and rehabilitation, it is a key construction hospital among Guangdong Province's high-level hospitals and one of the province's first high-level clinical medical colleges. It is also a member of the Guangzhou Research Hospital Alliance, the general hospital of the Tianhe District Urban Medical Group, and a designated medical institution under the "Hong Kong-Macao Drug and Device Connect" program. Since the national performance assessment of tertiary public hospitals began, it has ranked first in the country for consecutive years in the comprehensive group without annual reports.

Located in the Qianhai-Shekou Free Trade Zone of Shenzhen, Shenzhen Hospital, Southern Medical University is a municipal public comprehensive hospital jointly built by Southern Medical University (formerly the First Military Medical University) and the People's Government of Shenzhen Municipality. Fully operated and managed by Southern Medical University, the hospital leverages the university's strong disciplinary platforms and talent resources, guided by a development philosophy of "disciplines as the lead, medical quality as the core, talent cultivation as support, and warm service as a hallmark," providing high-level, warm medical services to residents of Shenzhen and the Guangdong-Hong Kong-Macao Greater Bay Area.

Founded in 1989, the First Affiliated Hospital of Shantou University Medical College is a provincial Grade-A tertiary comprehensive hospital directly under the Guangdong Provincial Health Commission, and the only provincial higher medical college affiliated hospital and provincial international medical pilot hospital in East Guangdong. Relying on the Shantou University Medical College, the hospital has a complete disciplinary system and national key clinical specialty construction projects, and has an international medical department providing high-quality international medical services for residents of East Guangdong and overseas Chinese of Chaoshan origin.

The University of Hong Kong-Shenzhen Hospital is a modern comprehensive Grade-A tertiary hospital fully funded by the Shenzhen Municipal Government and operated by the University of Hong Kong, and is the first public hospital in mainland China to adopt a "Hong Kong-style" modern hospital management model. The hospital fully introduces the medical technology and management experience of the University of Hong Kong and its affiliated Queen Mary Hospital, promoting internationally advanced concepts including appointment-based visits, team-based care, and holistic patient care. It has established an International Medical Center (IMC) providing high-quality medical services aligned with international standards for patients at home and abroad. Its cardiology, orthopedics, and hepatobiliary and pancreatic surgery departments are particularly strong, making it an important model of Shenzhen-Hong Kong medical cooperation.

Founded in 1999, Peking University Shenzhen Hospital is a modern Grade-A tertiary comprehensive hospital invested in by the Shenzhen Municipal Government and operated by Peking University Health Science Center. Leveraging the disciplinary and talent advantages of Peking University, the hospital brings the premium medical resources of "Beiyi" to Shenzhen, and is one of the youngest national Grade-A tertiary hospitals in the Shenzhen Special Economic Zone as well as an important window unit of Shenzhen's medical system. Its urology, stomatology center, and obstetrics and gynecology departments are distinctive, and its medical service level ranks among the top in Shenzhen.

Founded in 1946, Shenzhen People's Hospital is the oldest and largest municipal public Grade-A tertiary comprehensive hospital in Shenzhen. As an important medical center of the city, the hospital undertakes the city's primary medical, teaching, research, and health care tasks, and is also the Second Clinical Medical College of Jinan University and the First Affiliated Hospital of Southern University of Science and Technology. The hospital hosts platforms including the Shenzhen Clinical Medical Research Center and a national standardized residency training base, with multiple departments including respiratory medicine, orthopedics, and burn and plastic surgery wielding significant influence in South China, ranking among the top hospitals in Shenzhen.

Founded in 2001, Clifford Hospital, Guangdong (Clifford Hospital Affiliated with Jinan University) is the first comprehensive Grade-A tertiary hospital in China integrating traditional Chinese and Western medicine to receive international JCI accreditation, and a designated hospital for foreign-related medical services. Located in Clifford Estates, Panyu District, Guangzhou, the hospital integrates medical care, teaching, research, and preventive health, and has an international diagnosis and treatment center providing high-quality international medical services for compatriots from Hong Kong, Macao, Taiwan, and foreign visitors. Its oncology, gynecology, obstetrics, and cardiology departments are particularly strong, and its health screening services are very popular.

Founded in 1933, the Guangdong Provincial Hospital of Traditional Chinese Medicine (Second Affiliated Hospital of Guangzhou University of Chinese Medicine) is one of the earliest TCM hospitals in China's modern history, a Grade-A tertiary TCM hospital, and the largest TCM hospital in the country. Integrating medical care, teaching, research, and preventive health, the hospital is nationally leading in integrated Chinese and Western medicine with distinct TCM strengths, and houses specialized departments including rehabilitation medicine and a preventive health (Zhi Wei Bing) center. Its comprehensive strength has ranked among the top TCM hospitals in China for many consecutive years, with the highest annual outpatient volume among national TCM hospitals, and its rehabilitation medicine, acupuncture, and traumatology departments are renowned at home and abroad.

The Guangzhou Women and Children's Medical Center (Guangzhou Medical University) is the largest Grade-A tertiary women and children's specialty hospital in South China and among the first batch of public children's hospitals in China to receive JCI accreditation. The center operates multiple campuses including Zhujiang New Town, Children's Campus, and Maternal and Infant Campus, with annual outpatient volume ranking among the top women and children's specialty hospitals in the country. Its departments of obstetrics, pediatrics, neonatal surgery, pediatric hematology and oncology, and reproductive medicine are nationally leading, and the center has an international department providing internationalized, high-quality care for patients at home and abroad.

Founded in 1944, the Guangdong Provincial Maternal and Child Health Hospital (Guangdong Provincial Children's Hospital, Guangdong Provincial Obstetrics and Gynecology Hospital) is a Grade-A tertiary maternal and child health hospital directly under the Guangdong Provincial Health Commission, and is among the first batch of national-level demonstration bases for early childhood development and a national key specialty construction unit for pregnancy and childbirth care designated by the National Health Commission. As an important maternal and child health center in South China, the hospital has strong departments in obstetrics, pediatrics, neonatology, and assisted reproduction, with delivery volume consistently ranking among the top in the province for many years.